Last edited by Nilrajas
Monday, May 18, 2020 | History

5 edition of Interferon Alpha-2 found in the catalog.

Interferon Alpha-2

Pre-clinical and Clinical Evaluation (Developments in Oncology)

  • 106 Want to read
  • 28 Currently reading

Published by Springer .
Written in English

    Subjects:
  • Medical / Nursing,
  • Oncology,
  • Interferons,
  • Cancer Chemotherapy,
  • Medical,
  • Drugs,
  • Medical / Oncology,
  • Chemotherapy,
  • Cancer,
  • Congresses,
  • Evaluation,
  • Interferon

  • Edition Notes

    ContributionsDaniel L. Kisner (Editor), J.F. Smyth (Editor)
    The Physical Object
    FormatHardcover
    Number of Pages124
    ID Numbers
    Open LibraryOL8269623M
    ISBN 100898387019
    ISBN 109780898387018

    Human interferon alpha (hIFNα) is a wide biological activity cytokine that is used in hepatitis and cancer treatments. It regulates many genes that are involved in antiviral and antiproliferative. This article contains general information about the cytokine interferon alpha-2b (IFN-α2b). This protein is known to induce potent and diverse biological effects, and it has been clinically used.

    D. Mondal, in Reference Module in Biomedical Sciences, Introduction. Pegylated interferon alpha-2b is a covalent conjugate of recombinant interferon alpha-2b with mono-methoxy-polyethylene glycol (PEG) (Baker, ; Safrin, ).Interferon alpha-2b is a . Interferon alpha-2b remains to date the most promising approach available. Toxicities and intensive intravenous administration, unfortunately, are major concerns. An alternative is the use of interferon in its pegylated subcutaneous by: 9.

      Interferon alpha2 and interferon gamma induce the degranulation independent production of VEGF-A and IL-1 receptor antagonist and other mediators from human mast cells. Genetic mutation reduces the binding ability of interferon alpha 2 to the interferon receptor. A phase II trial of pegylated interferon alpha-2b therapy for polycythemia vera and essential thrombocythemia: feasibility, clinical and biologic effects, and impact on quality of life. Cancer. ; (11)– [Google Scholar]Cited by:


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Interferon Alpha-2 Download PDF EPUB FB2

Interferon alfa-2b is made from human proteins. Interferons help your body's immune system respond to bacteria, viruses, cancer, or other invading substances. Interferon alfa-2b is used to treat hairy cell leukemia, malignant melanoma, follicular lymphoma, Kaposi's sarcoma caused by AIDS, and certain types of genital eron alfa-2b is also used to treat chronic hepatitis B or C in / Interferon Alpha Pre-Clinical and Clinical Evaluation Book Subtitle Proceedings of the Symposium held in Adjunction with the Second International Conference on Malignant Lymphoma, Lugano, Switzerland, J   The first one was Beta Interferon in Japan, and the second one was the family of Alpha Interferon Interferon Alpha-2 book Genetec in California, according to the Cuban doctor.

"One year later in Cuba, we cloned different genes of Interferon from local sites, and we started to produce Interferon in andwhich we used in the outbreak of dengue fever, and we.

interferon alpha-2b until platelet or granulocyte counts return to normal or baseline levels, then reinstitute at 50% of dose. If granulocyte count /mm3 withinterferonalpha-2b,licularnon-Hodgkin’s lymphoma,ifgranulocytecount /mm3 orplateletco/mm3, Size: KB.

Time will tell if Interferon Alfa 2b proves to be the wonder drug as far as COVID goes. This article draws on material in my new book, We Are Cuba. How a. Interferon alfa-2a solution comes with an extra patient information sheet called a Medication Guide.

Read it carefully. Read it again each time Interferon Alpha-2 book get interferon alfa-2a solution refilled. Interferon alfa-2a solution is sometimes given as an injection at your doctor's office, hospital, or clinic.

Cuban Medical Brigades have deployed to dozens of countries around the world, providing life-saving personnel and products such as Interferon Alpha-2B Recombinant to battle the COVID coronavirus.

Interferon alfa-2a is in the FDA pregnancy category C. This means that it is not known whether interferon alfa-2a will be harmful to an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether interferon alfa-2a passes into breast milk. Interferon alfa-2b también se usa para el tratamiento de la hepatitis B o C crónica en los adultos y para tratar la hepatitis B crónica en los niños de al menos 1 año de edad. Interferon alfa-2b puede también usarse para fines no mencionados en esta guía del medicamento/ Pegylated interferon alfa-2a, sold under the brand name Pegasys among others, is medication used to treat hepatitis C and hepatitis B.

For hepatitis C it is typically used together with ribavirin and cure rates are between 24 and 92%. For hepatitis B it may be used alone. It is given by injection under the skin.

Side effects are common. They may include headache, feeling tired, depression Pregnancy category: C, X (with ribavirin). Interferons Alpha, Beta, and Omega Anthony Meager Biological Activities in vivo 6.

Receptors Characterization General Features Molecular Cloning of IFN Receptor Components by: Pegylated interferon alfa-2b, sold under the brand name PegIntron among others, is a medication used to treat hepatitis C and melanoma.

For hepatitis C it is typically used with ribavirin and cure rates are between 33 and 82%. For melanoma it is used in addition to surgery. It is given by injection under the skin. Side effects are common. They may include headache, feeling tired, mood changes Elimination half-life: 22–60 hrs.

Ribavirin and pegylated interferon-alpha-2 are the most commonly used drugs for HCV infections. Details on safety, efficacy, dosing, and warnings on these two drugs are provided on the package inserts, as cited (17, 18).

Two new drugs, telaprevir and boceprevir, were approved by the FDA in for use in combination with ribavirin and IFN.

Interferon alfa, when used in combination with ribavirin, must not be used during pregnancy by either the pregnant woman or her male partner.

The combination may cause harm to an unborn baby. Cuba’s Ministry of Public Health authorized the use of Cuban interferon to halt the dengue outbreak. It was done at great speed. Mortality declined. In their historical account, Cuban medical scientists Caballero Torres and Lopez Matilla wrote, “It was the most extensive prevention and therapy event with interferon carried out in the world.

Human interferon alpha is used in cats to treat FeLV, FIV, FIP, FHV-1 and a variety of dermatologic conditions. Studies support the use of oral human-interferon in cats for its immunomodulatory properties. Work in with FIV affected cats showed that the published low dose oral protocol improved both clinical signs and survival times.

Read "Interferon Alpha Pre-Clinical and Clinical Evaluation Proceedings of the Symposium held in Adjunction with the Second International Conference on Malignant Lymphoma, Lugano, Switzerland, J " by available from Rakuten Kobo. Interferon alpha-2 is a genetically engineered, highly pBrand: Springer US.

Interferon alfa 2b is an antiviral or antineoplastic drug, that was originally discovered in the laboratory of Charles Weissmann at the University of Zurich. It was developed at Biogen, and ultimately marketed by Schering-Plough under the tradename has been used for a wide range of indications, including viral infections and status: UK: POM (Prescription only), US: ℞-only.

Last week, reported that, for 40 years, Cuba has been using a molecule named Interferon Alpha 2B, which has successfully been used to combat the new Coronavirus in China and elsewhere. “The world has an opportunity to understand that health is not a commercial asset but a basic right,” Cuban doctor Luis Herrera, the creator of the Interferon Alfa 2-B medication, one of the.

Interferon alfa-2b is made from human proteins. Interferons help your body's immune system respond to bacteria, viruses, cancer, or other invading substances. Interferon alfa-2 is well absorbed following intramuscular (IM) or subcutaneous (SC) injection.

Peak serum interferon alfa-2 concentrations following intravenous (IV) administration of the drug generally occur within 15 to 60 minutes and are substantially greater than those attained after IM .Interferon alpha-2 is a genetically engineered, highly purified pharmaceutical agent that has undergone extensive phase I and phase II clinical study in more than patients.

The material has biological activity by intravenous, intramus­ cular and subcutaneous routes.Alpha interferon (IFN-alpha) is, to date, the only treatment with proven efficacy in patients with chronic hepatitis C.

However, less than 15% of the patients have a sustained response to IFN-alpha. Interferon acts through the induction of various cellular.